Abstract
Background
Abdominal surgery for gastrointestinal malignancies has a significant impact on patients'
health-related quality of life. However, there is so far no patient-reported outcome
measures (PROM) in the immediate postoperative period to detect the perioperative
symptom burden and patients’ needs which may precede occult and severe complications.
The aim of the study was to create a conceptual framework for the development of a
PROM to measure perioperative symptom burden in abdominal cancer patients.
Methods
This mixed method study was performed between March 2021, and July 2021 as part of
a multiphase approach to develop a new PROM. A systematic review of the literature
was performed health domains were identified. The relevance of the health domains
was assessed in a two-round Delphi study with clinical experts. Qualitative interviews
were performed in patients who underwent abdominal surgery for cancer.
Results
The systematic literature review yielded 12 different PROM with 168 items and 55 health
domains. The most common health domains involved the “digestive system” and “pain”.
In total, 30 patients (median age 66 years, 20 men [60%]) were included for qualitative
patient interviews. Of 16 health domains identified by the Delphi study, a total 15
health domains were confirmed during patients’ interviews. The final conceptual framework included 20 health domains.
Conclusion
This study provides the essential groundwork to develop and validate a new PROM for
the immediate postoperative period of patients undergoing abdominal surgery for cancer.
Keywords
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Article info
Publication history
Published online: May 17, 2023
Accepted:
May 8,
2023
Received in revised form:
May 1,
2023
Received:
April 11,
2023
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2023 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
