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The impact of the 30-day postoperative complications on the quality of life following gastrectomy for gastric carcinoma: A prospective study

  • Aelee Jang
    Affiliations
    Department of Nursing, University of Ulsan, Ulsan, South Korea
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  • Oh Jeong
    Correspondence
    Corresponding author. Department of Surgery, Chonnam National University Medical School, South Korea, 264, Seoyang-ro, Hwasun-eup, Hwasun-gun, Jeollanam-do, 58128, South Korea.
    Affiliations
    Department of Surgery, Chonnam National University Medical School, South Korea

    Division of Gastroenterologic Surgery, Chonnam National University Hwasun Hospital, South Korea
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Published:January 17, 2023DOI:https://doi.org/10.1016/j.ejso.2023.01.017

      Abstract

      Background

      The effect of postoperative complications on long-term quality of life (QoL) is controversial in abdominal surgery. This study aimed to investigate the impact of 30-day postoperative complications on long-term QoL after gastrectomy.

      Method

      This is a longitudinal cohort study that enrolled 908 patients undergoing gastrectomy for gastric cancer between 2016 and 2017. QoL was assessed using the European Organization for Research and Treatment of Cancer (EORTC) generic cancer (QLQ C-30) and gastric module (STO-22) preoperatively and at 1, 6, 12, and 24 months postoperatively. Patients were divided into the morbidity (30-day postoperative complications) and no-morbidity groups, and the postoperative QoL change was compared using a linear mixed model.

      Results

      The mean age was 62.5 ± 12.0 years. Subtotal and total gastrectomy was performed in 763 (84.0%) and 145 (16.0%) patients, respectively. There were 189 (20.8%) patients developing postoperative complications. The morbidity group showed worse scores in several functions and symptoms of QoL at the baseline. However, the two groups showed no significant difference in postoperative changes in most functions and symptoms of the QLQ C-30 and STO-22 (Pgroup × time > 0.05). The recovery of global health (Pgroup × time < 0.001) and anxiety (Pgroup × time = 0.008) was slightly better in the morbidity group. The subgroup analysis of patients developing major abdominal complications showed similar results.

      Conclusion

      The morbidity group showed worse QoL in several functions and symptoms at the baseline. However, postoperative complications had little influence on QoL change following gastrectomy for gastric cancer.

      Keywords

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