We thank Markopoulos and colleagues for their comments on our paper recently published
in the European Journal of Surgical Oncology on the prognostic impact of surgical
margin and tumor biology in patients who underwent surgical resection for colorectal
liver metastases [
[1]
].- Bohlok A.
- Inchiostro L.
- Lucidi V.
- Vankerckhove S.
- Hendlisz A.
- Van Laethem J.L.
- et al.
Tumor biology reflected by histological growth pattern is more important than surgical
margin for the prognosis of patients undergoing resection of colorectal liver metastases.
Eur J Surg Oncol. 2022; https://doi.org/10.1016/j.ejso.2022.08.006
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References
- Tumor biology reflected by histological growth pattern is more important than surgical margin for the prognosis of patients undergoing resection of colorectal liver metastases.Eur J Surg Oncol. 2022; https://doi.org/10.1016/j.ejso.2022.08.006
- Touch imprint intraoperative flow cytometry as a complementary tool for detailed assessment of resection margins and tumor biology in liver surgery for primary and metastatic liver neoplasms.Method Ptocol. 2021; 4: 66
- Detection of cancer cells and tumor margins during colorectal cancer surgery by intraoperative flow cytometry.Int J Surg. 2022; 106717
Article info
Publication history
Published online: October 24, 2022
Accepted:
October 17,
2022
Received:
October 12,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Impact of intraoperative flow cytometry in management of colorectal liver metastases: Simultaneous assessment of tumor biology and resection margin statusEuropean Journal of Surgical Oncology
- PreviewColorectal cancer is the third most common cancer in both men and women and approximately one third of patients develop liver metastases. Tumor free resection margins (R0 resection) is an important prognostic factor [1]. This can be due to surgical technique but mainly due to tumor biology, tumor burden and surgical complexity.
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