Abstract
Surveillance costs and appropriateness of surgery of “low-risk” BD-IPMNs are relevant
issues. In this study we evaluated the rate of correct indication for pancreatectomy
defined as high grade dysplasia (HGD) at histology in 961 patients who underwent surveillance
for a median of 5.1 years. Undertreatment and overtreatment were defined as invasive
cancer and low grade dysplasia (LGD) at histology, respectively. Of the 66 patients
(6.9%) who were operated, only 16 (23.8%) had a HGD while 40 (59.7%) had a LGD and
10 (14.9%) an invasive cancer, without differences regarding timing of surgery. The
mean surveillance cost was € 194.9 ± 107.6 per patient-year, with a median cost of
€ 277.1 ± 148.2 in the correct surgery group compared with € 222.7 ± 111.6 and € 197 ± 102.7
in the overtreatment and undertreatment groups. The surveillance mean cost from diagnosis
to surgery was € 854.8. Rate of appropriate surgery in BD-IPMNs under surveillance is low.
Keywords
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Article info
Publication history
Published online: August 30, 2022
Accepted:
August 26,
2022
Received in revised form:
June 22,
2022
Received:
May 13,
2022
Identification
Copyright
© 2022 Published by Elsevier Ltd.