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Trends in the surgical management of parapharyngeal space tumors: A single-center retrospective analysis

  • Author Footnotes
    1 Co-first authors, Xiaoke Zhu MD, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
    Xiaoke Zhu
    Footnotes
    1 Co-first authors, Xiaoke Zhu MD, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
    Search for articles by this author
  • Author Footnotes
    2 Xiaoling Shi MS, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
    Xiaoling Shi
    Footnotes
    2 Xiaoling Shi MS, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
    Search for articles by this author
  • Liang Zhou
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Ming Zhang
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Lei Cheng
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Yong Shi
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Chengzhi Xu
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Chunping Wu
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Quan Liu
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
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  • Pengyu Cao
    Correspondence
    Corresponding author. Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, PR China.
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
    Search for articles by this author
  • Lei Tao
    Correspondence
    Corresponding author. Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, PR China.
    Affiliations
    Department of Otolaryngology, Shanghai Key Clinical Disciplines of Otorhinolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai, PR China
    Search for articles by this author
  • Author Footnotes
    1 Co-first authors, Xiaoke Zhu MD, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
    2 Xiaoling Shi MS, Department of Otolaryngology, Eye Ear Nose & Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai 200031, PR China. E-mail: [email protected]
Published:August 18, 2022DOI:https://doi.org/10.1016/j.ejso.2022.08.016

      Abstract

      Purpose

      Surgery remains the mainstay treatment for parapharyngeal space (PPS) tumors. Given the rapid advance and increasing usage of endoscopic and robotic techniques, we aimed to investigate the surgical trends of PPS tumors in our institution and analyze their impact on patients’ treatment outcomes.

      Materials and methods

      All patients who underwent surgical resection of PPS tumors from 2014 to 2021 at the Eye, Ear, Nose, and Throat Hospital of Fudan University were retrospectively reviewed. Student's t-test, Chi-square test, and multinomial logistic regression analyses were used to compare the surgical outcomes between groups.

      Result

      Of the included 389 patients, the recipients of endoscopic surgery have largely increased in our center, with 17 of 134 cases (12.7%) in the group 2014–2017 and 187 of 255 cases (73.3%) in the group 2018–2021. The use of transoral and trans-nasal approaches increased in recent years (5.2% in 2014–2017 vs. 26.0% in 2018–2021), while that of trans-mandibular and lateral skull base approaches decreased (5.9% in 2014–2017 vs. 0.8% in 2018–2021). Decreased blood loss of operation and decreased risks of postoperative neurovascular complications were observed in the group 2018–2021. Similar findings were observed among patients receiving endoscopic surgery when compared with those receiving conventional surgery.

      Conclusion

      In our institution, the overall trends in the surgical management of PPS tumors moved towards minimally invasive approaches with the assistance of endoscopy or surgical robots. The two surgical techniques were feasible and safe, and to a great extent, contributed to the improved surgical outcomes we observed in recent years.

      Keywords

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