Abstract
Purpose
Surgery remains the mainstay treatment for parapharyngeal space (PPS) tumors. Given
the rapid advance and increasing usage of endoscopic and robotic techniques, we aimed
to investigate the surgical trends of PPS tumors in our institution and analyze their
impact on patients’ treatment outcomes.
Materials and methods
All patients who underwent surgical resection of PPS tumors from 2014 to 2021 at the
Eye, Ear, Nose, and Throat Hospital of Fudan University were retrospectively reviewed.
Student's t-test, Chi-square test, and multinomial logistic regression analyses were
used to compare the surgical outcomes between groups.
Result
Of the included 389 patients, the recipients of endoscopic surgery have largely increased
in our center, with 17 of 134 cases (12.7%) in the group 2014–2017 and 187 of 255
cases (73.3%) in the group 2018–2021. The use of transoral and trans-nasal approaches increased in recent years (5.2% in 2014–2017 vs. 26.0% in 2018–2021),
while that of trans-mandibular and lateral skull base approaches decreased (5.9% in 2014–2017 vs. 0.8%
in 2018–2021). Decreased blood loss of operation and decreased risks of postoperative
neurovascular complications were observed in the group 2018–2021. Similar findings
were observed among patients receiving endoscopic surgery when compared with those
receiving conventional surgery.
Conclusion
In our institution, the overall trends in the surgical management of PPS tumors moved
towards minimally invasive approaches with the assistance of endoscopy or surgical
robots. The two surgical techniques were feasible and safe, and to a great extent,
contributed to the improved surgical outcomes we observed in recent years.
Keywords
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Article info
Publication history
Published online: August 18, 2022
Accepted:
August 16,
2022
Received in revised form:
August 12,
2022
Received:
July 27,
2022
Identification
Copyright
© 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.