Currently, it remains an unmet need to accurately differentiate pancreatic mucinous
cysts (intraductal papillary mucinous neoplasm, IPMN) and mucinous cystic neoplasm
with underlying risk of progressing to malignancy [
[1]
,
[2]
]. Recently, in the report published by Y. Fujita et al., entitled Malignant potential and specific characteristics of pure main duct type intraductal
papillary mucinous neoplasm [
[3]
], the authors retrospectively analyzed clinicopathological characteristics incorporated
serum and pancreatic juice protein measurements, clinical and radiographic data from
1100 patients with IPMN (387 patients underwent surgery, 79 with main duct (MD) type,
146 with branch duct (BD) type and 162 with Mixed-type). This study found that mural
nodule height (≥5mm) and preoperative pancreatic juice CEA level (≥50ng/ml) were two
independent predictors for high-grade dysplasia (HGD) and invasive intraductal papillary
mucinous carcinoma (IPMC).To read this article in full you will need to make a payment
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References
- Precision surgery with the genetic assessment for operable pancreatic cancer beyond the radiological assessment alone.Hepatobiliary Surg Nutr. 2021; 10: 261-263https://doi.org/10.21037/hbsn-20-820
- Screening for pancreatic cancer-a compelling challenge.Hepatobiliary Surg Nutr. 2021; 10: 264-266https://doi.org/10.21037/hbsn-20-861
- Malignant potential and specific characteristics of pure main duct type intraductal papillary mucinous neoplasm.Eur J Surg Oncol. 2022; 48: 1054-1061https://doi.org/10.1016/j.ejso.2021.11.137
- Risk of the watch-and-wait concept in surgical treatment of intraductal papillary mucinous neoplasm.JAMA Surg. 2021; 156: 818-825https://doi.org/10.1001/jamasurg.2021.0950
Article info
Publication history
Published online: August 13, 2022
Accepted:
August 11,
2022
Received:
June 23,
2022
Identification
Copyright
© 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Malignant potential and specific characteristics of pure main duct type intraductal papillary mucinous neoplasmEuropean Journal of Surgical OncologyVol. 48Issue 5
- PreviewAs the malignant potential of main duct (MD-) type intraductal papillary mucinous neoplasm (IPMN) has been discussed together with Mixed-type in most previous studies, the malignant potential of pure MD-type IPMN remains unclear. This study evaluated the specific characteristics and predictors of high-grade dysplasia (HGD) and invasive intraductal papillary mucinous carcinoma (IPMC) for pure MD-type IPMN.
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