We would like to thank Dr Sun and colleagues [
[1]
] for their interest in our manuscript [
[2]
]. The authors correctly pointed out that there were significant differences in the
baseline clinicopathologic characteristics between the 3 age groups and suggested
that propensity-score matching (PSM) could be used to control for these baseline imbalances
[
- Tan L.L.Y.
- Chew V.T.W.
- Syn N.
- et al.
Effect of age on the short- and long-term outcomes of patients undergoing curative
liver resection for HCC.
Eur J Surg Oncol. 2021; https://doi.org/10.1016/j.ejso.2021.12.027
[1]
]. However, we would like to highlight that our study had already adjusted for confounding
biases using principal components analyses [
[3]
]. Propensity-score (PS) methodologies represent one of a very large array of statistical
approaches used to address confounding biases in observational cohorts. With regards
to the present study, PS methodologies, as a whole (not limited to PS matching [PSM],
but also other PS techniques as PS stratification [PSS], adjustment [PSA], and inverse
probability of treatment-weighting [IPTW]), may be inappropriate in the specific context
of our study for the following reasons.Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Surgical OncologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Does age effect on the short- and long-term outcomes of patients undergoing liver resection for hepatocellular carcinoma?.EJSO. 2021; (in press)
- Effect of age on the short- and long-term outcomes of patients undergoing curative liver resection for HCC.Eur J Surg Oncol. 2021; https://doi.org/10.1016/j.ejso.2021.12.027
- Simultaneous dimension reduction and adjustment for confounding variation.Proc Natl Acad Sci Unit States Am. 2016; 113 (Dec 20): 14662-14667
- Comparison between short and long-term outcomes after minimally invasive versus open liver resections for hepatocellular carcinoma: a 1:1 matched analysis.J Surg Oncol. 2021; 124: 560-571
- Impact of liver cirrhosis on the difficulty of minimally0invasive liver resections: a 1:1 coarsened exact-matched controlled study.Surg Endosc. 2021; 35: 5231-5238
- Perioperative outcomes of laparoscopic minor hepatectomy for hepatocellular carcinoma in the elderly.World J Surg. 2018; 42: 4063-4069
Article info
Publication history
Published online: January 07, 2022
Accepted:
January 4,
2022
Identification
Copyright
© 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Letter to editor: Does age effect on the short- and long-term outcomes of patients undergoing liver resection for hepatocellular carcinoma?European Journal of Surgical OncologyVol. 48Issue 4
- PreviewWith great interest we read the article by Tan and colleagues and congratulate the authors on their work describing the effect of age on the short- and long-term outcomes of patients with hepatocellular carcinoma (HCC) undergoing curative-intent liver resection [1]. In this retrospective study, length of postoperative hospital stay, postoperative complications and 90-day mortality, overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS) were analyzed and compared among three age groups: 764 young patients (<70 years), 278 septuagenarian patients (70–79 years) and 50 octogenarian patients (≥80 years).
- Full-Text
- Preview
