Abstract| Volume 43, ISSUE 12, P2385, December 2017

Undiagnosed primary hyperparathyroidism and recurrent miscarriage: A clinically significant risk? A pilot study

      Introduction: Primary hyperparathyroidism (pHPT) in pregnancy is reported to be associated with significant maternal and foetal complications and a 3-fold miscarriage risk. The prevalence of pHPT in women between 20-40 years is now known to be 1 in 2000 but the incidence of pHPT in pregnancy, complete and miscarried, is unknown and just 11 of 1200 parathyroidectomies performed over a 10-year period were on pregnant women in our department. Until now there was no published data on the prevalence of pHPT in the recurrent miscarriage (RM) population, defined by the WHO as ≥3 consecutive miscarriages and affecting 1% of couples trying to conceive. This is the first prospective study on pHPT in RM and aimed to assess its clinical significance.
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