Introduction: Primary hyperparathyroidism (pHPT) in pregnancy is reported to be associated with
significant maternal and foetal complications and a 3-fold miscarriage risk. The prevalence
of pHPT in women between 20-40 years is now known to be 1 in 2000 but the incidence
of pHPT in pregnancy, complete and miscarried, is unknown and just 11 of 1200 parathyroidectomies
performed over a 10-year period were on pregnant women in our department. Until now
there was no published data on the prevalence of pHPT in the recurrent miscarriage
(RM) population, defined by the WHO as ≥3 consecutive miscarriages and affecting 1%
of couples trying to conceive. This is the first prospective study on pHPT in RM and
aimed to assess its clinical significance.
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© 2017 Published by Elsevier Inc.