European Journal of Surgical Oncology
Volume 36, Issue 4 , Pages 378-383 , April 2010

Total femur replacement: Primary procedure for treatment of malignant tumours of the femur

  • S. Kalra

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK
  • ,
  • A. Abudu

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 0 121 685 4037; fax: +44 0 121 685 4146.
  • ,
  • H. Murata

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK
    • Department of Orthopaedics, Graduate School of Medical Science, Kyoto Perfectural University of Medicine, Kyoto, Japan
  • ,
  • R.J. Grimer

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK
  • ,
  • R.M. Tillman

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK
  • ,
  • S.R. Carter

      Affiliations

    • Royal Orthopaedic Hospital NHS Trust, Bristol Road South, Birmingham B31 2AP, England, UK

,Accepted 5 November 2009.

References 

  1. Grimer RJ, Carter SR, Pynsent PB. The cost-effectiveness of limb salvage for bone tumours. J Bone Joint Surg Br. 1997;79-B(4):558–561
  2. Otis JC, Lane JM, Kroll MA. Energy cost during gait in osteosarcoma patients after resection and knee replacement and after above-knee amputation. J Bone Joint Surg Am. 1985;67-A(4):606–610
  3. Gebhardt MC, Goorin A, Traina J, et al. Long-term results of limb salvage and amputation in extremity osteosarcoma. In:  Yamamuro T editors. New developments for limb salvage in musculoskeletal tumours. New York: Springer; 1989;p. 99–109
  4. Buchman J. The femur and knee joint replacement with a vitallium endoprosthesis. Bull Hosp Joint Dis. 1965;26:21–34
  5. Mankin HJ, Gebhardt MC, Jennings LC, et al. Long-term results of allograft replacement in the management of bone tumours. Clin Orthop. 1996;324:86–97
  6. Marcove R, Lewis M, Rosen G, Huvos AG. Total femur and total knee replacement. Clin Orthop. 1977;126:147–152
  7. Morris HG, Capanna R, Campanacci M, Del Ben M, Gasbarrini A. Modular endoprosthetic replacement after total resection of the femur for malignant tumour. Intern Orthop. 1994;18:90–95
  8. Nerubay J, Katznelson A, Tichler T, et al. Total femoral replacement. Clin Orthop. 1988;229:143–148
  9. Ottolenghi C. Massive Osteoarticular bone grafts: transplant of the whole femur. J Bone Joint Surg Br. 1966;48-B:646–659
  10. Steinbrink K, Engelbrecht E, Fenelon G. The total femoral prosthesis: a preliminary report. J Bone Joint Surg Br. 1982;64-B:305–312
  11. Hardes J, Gosheger G, Vachtsevanos L, Hoffmann C, Ahrens H, Winkelmann W. Rotationplasty type B1 versus type BIIIa in children under age of ten years. Should the knee be preserved?. J Bone Joint Surg Br. 2005;87(3):395–400
  12. Winkelmann WW. Type-B-IIIa rotationplasty: an alternative operation for the treatment of malignant tumors of the femur in early childhood. J Bone Joint Surg Am. 2000;82(6):814–828
  13. Enneking WF, Spanier SS, Goodman MA. A system for the surgical staging of musculoskeletal sarcoma. Clin Orthop. 1980;153:106–119
  14. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457–481
  15. Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumours of the musculoskeletal system. Clin Orthop. 1993;286:241–245
  16. Davis AM, Wright JI, Williams C, Bombardier C, Griffin A, Bell RS. Development of a measure of physical function for patients with bone and soft tissue sarcoma. Quality of Life Research. 1996;5:508–516
  17. Rougraff BT, Simon MA, Kneisl JS, Greenberg DB, Mankin HJ. Limb salvage compared with amputation of osteosarcoma of the distal femur. J Bone Joint Surg Am. 1994;76-A(5):649–656
  18. Horowitz SM, Glasser DB, Lane JM, Healey JH. Prosthetic and extremity survivorship after limb salvage for sarcomas: How long do the reconstructions last?. Clin Orthop. 1993;293:280–286
  19. Zeegen EN, Aponte-Tinao LA, Hornicek FJ, Gebhardt MC, Mankin HJ. Survivorship analysis of 141 modular metallic endoprostheses at early followup. Clin Orthop. 2004;420:239–250
  20. Schindler OS, Cannon SR, Briggs TWR, et al. Use of extendable total femoral replacements in children with malignant bone tumours. Clin Orthop Relat Res. 1998;357:157–170
  21. Berend KR, Lombardi AV, Mallory TH, Adams JB, Dodds KL. Total femoral arthroplasty for salvage of end-stage prosthetic disease. Clin Orthop Relat Res. 2004;427:162–170
  22. Simon MA, Nachman J. The clinical utility of preoperative therapy for sarcomas. J Bone Joint Surg Am. 1986;68-A:1458–1463
  23. Grimer RJ, Taminiau AM, Cannon SR. Surgical outcomes in osteosarcoma. J Bone Joint Surg Br. 2002;84-B:395–400
  24. Present DA, Kuschner SH. Total femur replacement. A case report with 35-year followup study. Clin Orthop Relat Res. 1990;251:166–167
  25. Ward WG, Yang RS, Eckardt JJ. Total femoral endoprosthetic reconstruction. Clin Orthop Relat Res. 1995;316:195–206
  26. Mankin HJ, Hornicek FJ, Harris M. Total femur replacement procedures in tumor treatment. Clin Orthop Relat Res. 2005;438:60–64
  27. Friesecke C, Plutat J, Block A. Revision arthroplasty with use of a total femur prosthesis. J Bone Joint Surg Am. 2005;87(12):2693–2701
  28. Ahlmann ER, Menendez LR, Kermani C, Gotha H. Survivorship and clinical outcome of modular endoprosthetic reconstruction for neoplastic disease. J Bone Joint Surg Br. 2006;88-B:790–795

 Level of Evidence – Therapeutic Study, Level – IV (Case series).

PII: S0748-7983(09)00504-6

doi: 10.1016/j.ejso.2009.11.002

European Journal of Surgical Oncology
Volume 36, Issue 4 , Pages 378-383 , April 2010