European Journal of Surgical Oncology
Volume 36, Issue 2 , Pages 160-163 , February 2010

Human papillomavirus type 16 E6 gene variations in Chinese population

  • H.B. Cai

      Affiliations

    • Department of Gynecologic Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan 430071, PR China
    • Corresponding Author InformationCorrespondence to: Dr. H.B. Cai, Department of Gynecologic Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, PR China. Tel.: +86 27 67812648; fax: +86 27 67813044.
    • ,
  • C.C. Chen

      Affiliations

    • Department of Gynecologic Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuhan 430071, PR China
    • ,
  • X.H. Ding

      Affiliations

    • Institute of Virology, Wuhan University, Wuhan 430071, PR China

,Accepted 31 July 2009.

References 

  1. Lo K, Wong TF, Chan MK, et al. Prevalence of human papillomavirus in cervical cancer: a multicenter study in China. Int J Cancer. 2002;100(3):327–331
  2. Bosch FX, Manos MM, Munos M, et al. Prevalence of human papillomavirus in cervical cancer: a world perspective. J Natl Cancer Inst. 1995;87:798–802
  3. Zehbe I, Voglino G, Delius H, Wilander E, Tommasino M. Risk of cervical cancer and geographical variations of human papillomavirus 16 E6 polymorphisms. Lancet. 1998;352:1441–1442
  4. Matsumoto K, Yoshikawa H, Nakagawa S, et al. Enhanced oncogenicity of human papillomavirus type 16 (HPV16) variants in Japanese population. Cancer Lett. 2000;156:159–165
  5. Andersson S, Alemi M, Rylander E. Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions. Br J Cancer. 2000;83:307–310
  6. Londesborough P, Ho L, Terry G. Human papillomavirus genotype as a predictor of persistence and development of high-grade lesions in women with minor cervical abnormalities. Int J Cancer. 1996;69:364–368
  7. Berumen J, Ordonez RM, Lazcano E. Asian-American variants of human papillomavirus 16 and risk for cervical cancer: a case–control study. J Natl Cancer Inst. 2001;93:1325–1330
  8. Zehbe I, Wilander E, Delius H, Tommasino M. Human papillomavirus 16 E6 variants are more prevalence in invasive cervical carcinoma than the prototype. Cancer Res. 1998;58:829–833
  9. Kang S, Jeon YT, Kim JW, et al. Polymorphism in the E6 gene of human papillomavirus type 16 in the cervical tissues of Korean women. Int J Gynecol Cancer. 2005;15:107–109
  10. Stephen AL, Thompson CH, Tattersall MH, Cossart YE, Rose RB. Analysis of mutations in the URR an E6/E7 oncogenes of HPV 16 cervical cancer isolates from central China. Int J Cancer. 2000;86:695–701
  11. Zhang JM. The distribution and characteristic of carcinoma of the cervix uteri in Lue Yang country. Zhonghua Liu Xing Bing Xue Za Zhi. 1986;7:343–345
  12. Villa LL, Sichero L, Rahal P, et al. Molecular variants of human papillomavirus types 16 and 18 preferentially associated with cervical neoplasia. J Gen Virol. 2000;81:2959–2968
  13. Clifford GM, Smith JS, Plummer M, Muñoz N, Franceschi S. Human papillomavirus types in invasive cervical cancer worldwide: a meta-analysis. Br J Cancer. 2003;88:36–73
  14. Cai HB, Ding XH, Zhou YF, Lie D. Risk factors for cervical cancer in China: a case–control study. Eur J Gynaecol Oncol. 2008;XXIX:72–75
  15. Yamada T, Manos M, Peto J, et al. Human papillomavirus type 16 sequence variation in cervical cancers: a worldwide prospective. J Virol. 1997;71:2463–2482
  16. Nindl I, Rindfleisch K, Lotz B, Schneider A, Durst M. Uniform distribution of HPV 16 E6 and E7 variants in patients with normal histology, cervical intra-epithelial neoplasia and cervical cancer. Int J Cancer. 1999;82:203–207
  17. Hu X, Guo Z, Tianyun P. HPV typing and HPV16 E6-sequence variations in synchronous lesions of cervical squamous-cell carcinoma from Swedish patients. Int J Cancer. 1999;83:34–37
  18. Sichero L, Villa LL. Epidemiological and functional implications of molecular variants of human papillomavirus. Braz J Med Biol Res. 2006;39:707–717

PII: S0748-7983(09)00411-9

doi: 10.1016/j.ejso.2009.07.186

European Journal of Surgical Oncology
Volume 36, Issue 2 , Pages 160-163 , February 2010

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