European Journal of Surgical Oncology
Volume 35, Issue 11 , Pages 1146-1151 , November 2009

Surgical resection of the primary tumour is associated with improved survival in patients with distant metastatic breast cancer at diagnosis

  • J. Ruiterkamp

      Affiliations

    • Department of Surgery, Jeroen Bosch Hospital, PO Box 90153, 5200 ME ‘s-Hertogenbosch, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 (0)73 699 2701; fax: +31 (0)73 699 2163.
    • ,
  • M.F. Ernst

      Affiliations

    • Department of Surgery, Jeroen Bosch Hospital, PO Box 90153, 5200 ME ‘s-Hertogenbosch, The Netherlands
    • ,
  • L.V. van de Poll-Franse

      Affiliations

    • Comprehensive Cancer Centre South, Eindhoven, The Netherlands
    • CoRPS - Center of Research in Somatic Diseases, Department of Medical Psychology, Tilburg University, The Netherlands
    • ,
  • K. Bosscha

      Affiliations

    • Department of Surgery, Jeroen Bosch Hospital, PO Box 90153, 5200 ME ‘s-Hertogenbosch, The Netherlands
    • ,
  • V.C.G. Tjan-Heijnen

      Affiliations

    • Department of Medical Oncology, Maastricht University Medical Centre, Research Institute Growth and Development (GROW), Maastricht, The Netherlands
    • ,
  • A.C. Voogd

      Affiliations

    • Department of Epidemiology, Maastricht University Medical Centre, Research Institute Growth and Development (GROW), Maastricht, The Netherlands

,Accepted 30 March 2009.

References 

  1. Khan SA, Stewart AK, Morrow M. Does aggressive local therapy improve survival in metastatic breast cancer?. Surgery. 2002;132:620–626(discussion 6–7)
  2. Gnerlich J, Jeffe DB, Deshpande AD, Beers C, Zander C, Margenthaler JA. Surgical removal of the primary tumor increases overall survival in patients with metastatic breast cancer: analysis of the 1988–2003 SEER data. Ann Surg Oncol. 2007;14:2187–2194
  3. Rapiti E, Verkooijen HM, Vlastos G, et al. Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis. J Clin Oncol. 2006;24:2743–2749
  4. Fields RC, Jeffe DB, Trinkaus K, et al. Surgical resection of the primary tumor is associated with increased long-term survival in patients with stage IV breast cancer after controlling for site of metastasis. Ann Surg Oncol. 2007;14:3345–3451
  5. Babiera GV, Rao R, Feng L, et al. Effect of primary tumor extirpation in breast cancer patients who present with stage IV disease and an intact primary tumor. Ann Surg Oncol. 2006;13:776–782
  6. Blanchard DK, Shetty PB, Hilsenbeck SG, Elledge RM. Association of surgery with improved survival in stage IV breast cancer patients. Ann Surg. 2008;247:732–738
  7. In:  Hermanek P,  Sobin LH editor. UICC TNM classification of malignant tumours. Berlin: Springer-Verlag; 1987;p. 94–99
  8. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–383
  9. Coebergh JW, Janssen-Heijnen ML, Post PN, Razenberg PP. Serious co-morbidity among unselected cancer patients newly diagnosed in the southeastern part of The Netherlands in 1993–1996. J Clin Epidemiol. 1999;52:1131–1136
  10. Cady B, Nathan NR, Michaelson JS, Golshan M, Smith BL. Matched pair analyses of stage IV breast cancer with or without resection of primary breast site. Ann Surg Oncol. 2008;15:3384–3395
  11. Cristofanilli M, Budd GT, Ellis MJ, et al. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N Engl J Med. 2004;351:781–791
  12. Khan SA. Primary tumor resection in stage IV breast cancer: consistent benefit, or consistent bias?. Ann Surg Oncol. 2007;14:3285–3287

☆ This paper was presented at the 14th International Congress of the European Society of Surgical Oncology held from 10th to 12th September, 2008. The abstract was one of the highest scoring papers as judged by the Scientific Committee.

PII: S0748-7983(09)00117-6

doi: 10.1016/j.ejso.2009.03.012

European Journal of Surgical Oncology
Volume 35, Issue 11 , Pages 1146-1151 , November 2009

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