European Journal of Surgical Oncology
Volume 35, Issue 10 , Pages 1085-1091 , October 2009

Accuracy of liver-specific magnetic resonance imaging as a predictor of chemotherapy-associated hepatic cellular injury prior to liver resection

  • T.R. O'Rourke

      Affiliations

    • Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, United Kingdom
    • ,
  • F.K.S. Welsh

      Affiliations

    • Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, United Kingdom
    • ,
  • P.P. Tekkis

      Affiliations

    • Department of Biosurgery and Surgical Technology, Chelsea and Westminster Hospital, Imperial College, London, United Kingdom
    • ,
  • N. Lyle

      Affiliations

    • Department of Radiology, Basingstoke and North Hampshire Foundation Trust, Basingstoke, United Kingdom
    • ,
  • A. Mustajab

      Affiliations

    • Department of Pathology, Basingstoke and North Hampshire Foundation Trust, Basingstoke, United Kingdom
    • ,
  • T.G. John

      Affiliations

    • Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, United Kingdom
    • ,
  • D. Peppercorn

      Affiliations

    • Department of Radiology, Basingstoke and North Hampshire Foundation Trust, Basingstoke, United Kingdom
    • ,
  • M. Rees

      Affiliations

    • Department of Hepatobiliary Surgery, Basingstoke and North Hampshire Foundation Trust, Aldermaston Road, Basingstoke, Hampshire RG24 9NA, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 1256 313558; fax: +44 1256 313532.

,Accepted 28 January 2009.

References 

  1. Stangl R, Altendorf-Hofmann A, Charnley RM, Scheele J. Factors influencing the natural history of colorectal liver metastases. Lancet. 1994;343:1405–1410
  2. Scheele J, Stang R, Altendorf-Hofmann A, Paul M. Resection of colorectal liver metastases. World J Surg. 1995;19:59–71
  3. Rees M, Plant G, Bygrave S. Late results justify resection for multiple hepatic metastases from colorectal cancer. Br J Surg. 1997;84:1136–1140
  4. Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH. Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg. 1999;230:309–318
  5. de Gramont A, Figer A, Seymour M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol. 2000;18:2938–2947
  6. Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet. 2000;355:1041–1047
  7. Adam R. Colorectal cancer with synchronous liver metastases. Br J Surg. 2007;94:129–131
  8. Bismuth H, Adam R, Levi F, et al. Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy. Ann Surg. 1996;224:509–520
  9. Rubbia-Brandt L, Audard V, Sartoretti P, et al. Severe sinusoidal obstruction associated with oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer. Ann Oncol. 2004;15:460–466
  10. Vauthey JN, Pawlik TM, Ribero D, et al. Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol. 2006;23:2065–2072
  11. Nordlinger B, Sorbye H, Debois M, et al. Feasibility and risks of pre-operative chemotherapy (CT) with folfox 4 and surgery for respectable colorectal cancer liver metastases (LM). Interim results of the EORTC intergroup randomised phase III study 40983. J Clin Oncol. 2005;23:3528
  12. Welsh FK, Tilney HS, Tekkis PP, John TG, Rees M. Safe liver resection following chemotherapy for colorectal metastases is a matter of timing. Br J Cancer. 2007;96:1037–1042
  13. Fong Y, Bentrem DJ. CASH (chemotherapy-associated steatohepatitis) costs. Ann Surg. 2006;243:8–9
  14. Karoui M, Penna C, Amin-Hashem M, et al. Influence of preoperative chemotherapy on the risk of major hepatectomy for colorectal liver metastases. Ann Surg. 2006;243:1–7
  15. Zorzi D, Laurent A, Pawlick TM, Lauwers GY, Vauthey JN, Abdalla EK. Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases. Br J Surg. 2007;94:274–286
  16. Vetelainen R, Van Vilet A, Gouma DJ, Van Gulik TM. Steatosis as a risk factor in liver surgery. Ann Surg. 2007;245:20–30
  17. Rinella ME, McCathy R, Thakrar K, et al. Dual-echo, chemical shift gradient-echo magnetic resonance imaging to quantify hepatic steatosis: implications for living liver donation. Liver Transpl. 2003;9:851–856
  18. Cho CS, Curran S, Schwartz LH, Kooby DA, Klimstra DS, Shia DS, et al. Preoperative radiological assessment of hepatic steatosis with histological correlation. J Am Coll Surg. 2008;206:480–488
  19. Rees M, Tekkis PP, Welsh FK, O'Rourke T, John TG. A prospective evaluation of long-term survival following hepatic resection for metastatic colorectal cancer – a multifactorial model of 929 patients. Ann Surg. 2008;247:125–135
  20. Strasberg SM, Belghiti J, Clavien PA, et al. Terminology of liver anatomy and resections. HPB. 2000;2:333–339
  21. Ward J, Robinson PJ, Guthrie JA, et al. Liver metastases in candidates for hepatic resection: comparison of helical CT and gadolinium- and SPIO-enhanced MR imaging. Radiology. 2005;237:170–180
  22. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313–1321
  23. Adam R, Pascal G, Castaing D, et al. Tumor progression while on chemotherapy: a contraindication to liver resection for multiple colorectal metastases?. Ann Surg. 2004;240:1052–1061
  24. Kooby DA, Fong Y, Suriawinata A, et al. Impact of steatosis on perioperative outcome following hepatic resection. J Gastrointest Surg. 2003;7:1034–1044
  25. Peppercorn PD, Rezneck RH, Wilson P, Slevin ML, Gupta RK. Demonstration of hepatic steatosis by computerized tomography in patients receiving 5-flurouracil-based therapy for advanced colorectal cancer. Br J Cancer. 1998;77:2008–2011
  26. McCormack L, Petrowsky H, Jochum W, Furrer K, Clavien PA. Hepatic steatosis is a risk factor for postoperative complications after major hepatectomy. Ann Surg. 2007;245:923–930
  27. Jones OM, Rees M, John TG, Bygrave S, Plant GR. Biopsy of resectable colorectal liver metastases causes tumour dissemination and adversely affects survival after liver resection. Br J Surg. 2005;92:1165–1168
  28. Ward J, Guthrie JA, Sheridan MB, et al. Sinusoidal obstructive syndrome diagnosed with superparamagnetic iron oxide-enhanced magnetic resonance imaging in patients with chemotherapy-treated colorectal liver metastases. J Clin Oncol. 2008;26:4304–4310
  29. wasaki M, Takada Y, Hayashi M, et al. Noninvasive evaluation of graft steatosis in living donor liver transplantation. Transplantation. 2004;78:1501–1505
  30. Karcaaltincaba M, Akhan O. Imaging of hepatic steatosis and fatty sparing. Eur J Radiol. 2007;61:33–43
  31. Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology. 2006;43:S99–S112
  32. Powell EE, Jonsson JR, Clouston AD. Steatosis: co-factor in other liver disease. Hepatology. 2005;42:5–13
  33. Azoulay D, Castaing D, Smail A, et al. Resection of nonresectable liver metastases from colorectal cancer after percutaneous portal vein embolization. Ann Surg. 2000;231:480–486
  34. Nakamuta M, Morizono S, Soejima Y, et al. Short-term intensive treatment for donors with hepatic steatosis in living-donor liver transplantation. Transplantation. 2005;80:608–612
  35. Fris RJ. Preoperative low energy diet diminishes liver size. Obes Surg. 2004;14:1165–1170
  36. Musso G, Gambino R, Durazzo M, et al. Adipokines in NASH: postprandial lipid metabolism as a link between adiponectin and liver disease. Hepatology. 2005;42:1175–1183

PII: S0748-7983(09)00034-1

doi: 10.1016/j.ejso.2009.01.015

European Journal of Surgical Oncology
Volume 35, Issue 10 , Pages 1085-1091 , October 2009

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