« Previous
Next »
European Journal of Surgical Oncology
Volume 35, Issue 1
, Pages 3-10
, January 2009
The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors)
References
- . Desmoid tumoren bij patienten met familiaire adenomateuze polyposis. NTvG. 2002;146(29):1355–1359
- . Turrisi AT III. Surgery versus radiation therapy for patients with aggressive fibromatosis or desmoid tumor. Cancer. 2000;88:1517–1523
- Extraabdominal desmoid tumor. Clin Orthop Res. 2000;375:207–213
- . Extra-abdominal desmoid tumour of the breast: review of the primary management and the implications for breast reconstruction. Br J Plast Surg. 2001;54(3):268–271
- Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene. Am J Hum Genet. 1996;59(6):1193–1201
- . Familial infiltrative fibromatosis (desmoid tumours) (MIM135290) caused by a recurrent 3′ APC gene mutation. Hum Mol Genet. 1996;5(12):1921–1924
- . Comprehensive genetic and endoscopic evaluation may be necessary to distinguish sporadic versus familial adenomatous polyposis-associated abdominal desmoid tumors. Surgery. 2004;135(6):683–689
- 3′ Mutation of the APC gene and family history of FAP in a patient with apparently sporadic desmoid tumors. J Clin Gastroenterol. 2007;41(3):297–300
- Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution. J Clin Oncol. 2006;21(7):1390–1397
- . Extremity and trunk desmoid tumors: a multifactorial analysis of outcome. Cancer. 1999;86:2045–2052
- Optimizing treatment of desmoid tumors. J Clin Oncol. 2007;25(13):1785–1791
- Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor). J Clin Oncol. 2006;24(7):1195–1203
- Low-dose chemotherapy with methotrexate and vinblastine for patients with advanced aggressive fibromatosis. Cancer. 2001;92(5):1259–1264
- Desmoid tumors in a dutch cohort of patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008;6(2):215–219
- Expression profiles of sex steroid receptors in desmoid tumors. Tohoku J Exp Med. 2006;210(3):189–198
- . Estrogen receptor-beta expression in extraabdominal fibromatoses: an analysis of 40 cases. Cancer. 2006;106(1):208–213
- . Desmoid fibromatosis is a clonal process. Hum Pathol. 1996;27(9):939–943
- A gene expression signature that distinguishes desmoid tumours from nodular fasciitis. J Pathol. 2006;208:543–553
- . Van der Heul RO. Desmoplastic fibroma of bone: a report of 18 cases. Skelet Radiol. 1994;23:283–288
- Characterization of molecular abnormalities in human fibroblastic neoplasms: a model for genotype-phenotype association in soft tissue tumors. Cancer Res. 2001;61(April 1):3171–2175
- . Chromosome aberrations in desmoid tumors. Cancer Genet Cytogenet. 1995;79(139):143
- . Clinicopathological and interphase cytogenetic analysis of desmoid tumors. Histopathology. 1997;31:336–341
- Trisomies 8 and 20 characterize a subgroup of benign fibrous lesions arising in both soft tissue and bone. Am J Pathol. 1999;154:729–733
- Clonal X-inactivation analysis of human tumours using the human androgen receptor gene (HUMARA) polymorphism: a non-radioactive and semiquantitative strategy applicable to fresh and archival tissue. Mol Cell Probes. 1997;11(3):217–228
- . Molecular genetic and immunohistochemical analysis of the tumor suppressor genes Rb and P53 in palmar and aggressive fibromatosis. Diag Mol Pathol. 1996;5(3):194–200
- . Van der Houven van Oordt W, Luz A, et al. Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts. Gastroenterology. 1998;114:275–283
- . The molecular and genetic basis of colon cancer. Med Clin North Am. 2002;86(6):1467–1495
- Ki-67 expression and residual tumour (R) classification are associated with disease-free survival in desmoid tumour patients. Anticancer Res. 2001;21(5):3615–3620
- Expression of beta-catenin and p53 are prognostic factors in deep aggressive fibromatosis. Histopathology. 2007;50(4):491–497
- . Desmoid tumours complicating familial adenomatous polyposis. Br J Surg. 1999;86(9):1185–1189
- A germline mutation at the extreme 3′ end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor. Clin Genet. 2000;57:205–212
- . Desmoids tumours in familial adenomatous polyposis. Gut. 1994;35:377–381
- . A 10-year review of surgery for desmoid disease associated with familial adenomatous polyposis. Br J Surg. 2006;93:1258–1264
- . Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations. Br J Surg. 2007;94(8):1009–1013
- The APC gene product in normal and tumor cells. Proc Natl Acad Sci USA. 1993;90(7):2846–2850
- The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's ‘two-hit’ hypothesis. Nat Med. 1999;5(9):1071–1075
- Genotype and phenotype factors as determinants of desmoid tumors in patients with familial adenomatous polyposis. Int J Cancer. 2001;95:102–107
- . Mom1 is a semi-dominant modifier of intestinal adenoma size and multiplicity in Min/+ mice. Genetics. 1996;144(4):1769–1776
- . Loss of APC heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated APC gene. Proc Natl Acad Sci USA. 1995;92(10):4482–4486
- Apc1638T: a Mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes Dev. 1999;13(10):1309–1321
- Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science. 1992;256(5057):668–670
- . a negative regulator of the wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J. 1998;17(5):1371–1384
- Constitutive transcriptional activation by a beta-catenin–tcf complex in APC−/− colon carcinoma. Science. 1997;275:1784–1787
- Activation of beta-catenin–tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275(5307):1787–1790
- Identification of C-MYC as a target of the APC pathway. Science. 1998;281(5382):1509–1512
- The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell. 2002;111(2):241–250
- Possible association between higher beta-catenin mRNA expression and mutated beta-catenin in sporadic desmoid tumors: real-time semiquantitative assay by TaqMan polymerase chain reaction. Lab Invest. 2002;82(1):97–103
- The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies. Cytogenet Cell Genet. 1995;71(4):343–344
- Coexistence of somatic and germ-line mutations of APC gene in desmoid tumors from patients with familial adenomatous polyposis. Cancer Res. 1993;53(21):5079–5082
- . Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatosis (desmoid tumor). Am J Pathol. 1997;151:329–334
- . Frequent mutations in the beta-catenin gene in desmoid tumors from patients without familial adenomatous polyposis. Oncol Res. 1998;10(11-12):591–594
- Analysis of Wnt/beta catenin signalling in desmoid tumors. Acta Gastroenterol Belg. 2005;68(1):5–9
- Genetic testing for germline mutations of the APC gene in patients with apparently sporadic desmoid tumors but a family history of colorectal carcinoma. Dis Colon Rectum. 2005;48(6):1275–1281
- Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumors. Br J Cancer. 1998;78(5):582–587
- . Adenomatous polyposis coli gene mutation alters proliferation through its beta-catenin-regulatory function in aggressive fibromatosis (desmoid tumor). Am J Pathol. 1998;153(3):709–714
- A novel case of a sporadic desmoid tumour with mutation of the beta-catenin gene. J Clin Pathol. 1999;52:695–696
- Cyclooxygenase-Two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor). Oncogene. 2001;20(4):451–460
- Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor). Oncogene. 1999;18(47):6615–6620
- Intrathoracic sporadic desmoid tumor with the beta-catenin gene mutation in exon 3 and activated cyclin D1. Respiration. 2006;73(4):558–561
- Beta-catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds. Proc Natl Acad Sci USA. 2002;99(10):6973–6978
- . Deletion (5q) in a desmoid tumor of patient with Gardner's syndrome. Cancer Genet Cytogenet. 1994;78(1):94–98
- Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation. Gut. 2004;53(12):1832–1836
- germline mutations in the 3′ part of APC Exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli. Hum Genet. 1996;98(6):727–734
- Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers. Proc Natl Acad Sci USA. 2000;97(7):3461–3466
- Human sterile alpha motif domain 9, a novel gene identified as down-regulated in aggressive fibromatosis, is absent in the mouse. BMC Genomics. 2007;8(92):
- . Multifocal desmoids. Surgery. 1993;114:902–906
PII: S0748-7983(08)01709-5
doi: 10.1016/j.ejso.2008.07.003
© 2008 Elsevier Ltd. All rights reserved.
« Previous
Next »
European Journal of Surgical Oncology
Volume 35, Issue 1
, Pages 3-10
, January 2009
