European Journal of Surgical Oncology
Volume 35, Issue 2 , Pages 164-167 , February 2009

Primary tumour resection and survival in the palliative management of metastatic colorectal cancer

  • A. Bajwa

      Affiliations

    • Colorectal Unit, Department of Surgery, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK
    • ,
  • N. Blunt

      Affiliations

    • Colorectal Unit, Department of Surgery, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK
    • ,
  • S. Vyas

      Affiliations

    • Colorectal Unit, Department of Surgery, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK
    • ,
  • I. Suliman

      Affiliations

    • Colorectal Unit, Department of Surgery, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK
    • ,
  • J. Bridgewater

      Affiliations

    • Department of Oncology, University College London and University College London Hospitals, London, UK
    • ,
  • D. Hochhauser

      Affiliations

    • Department of Oncology, University College London and University College London Hospitals, London, UK
    • ,
  • J.A. Ledermann

      Affiliations

    • Department of Oncology, University College London and University College London Hospitals, London, UK
    • ,
  • A. O'Bichere

      Affiliations

    • Colorectal Unit, Department of Surgery, University College London Hospitals, 235 Euston Road, London, NW1 2BU, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 (0)207 380 9454; fax: +44 (0)207 380 9312.

,Accepted 2 June 2008.

References 

  1. Cook AD, Single R, McCahill LE. Surgical resection of primary tumors in patients who present with stage IV colorectal cancer: an analysis of surveillance, epidemiology, and end results data, 1988 to 2000. Ann Surg Oncol. 2005;12(8):637–645
  2. Martin R, Paty P, Fong Y, et al. Simultaneous liver and colorectal resections are safe for synchronous colorectal liver metastasis. J Am Coll Surg. 2003;197(2):233–241
  3. Zampino MG, Magni E, Massacesi C, et al. First clinical experience of orally active epidermal growth factor receptor inhibitor combined with simplified FOLFOX6 as first-line treatment for metastatic colorectal cancer. Cancer. 2007;110(4):752–758
  4. Tournigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004;22(2):229–237
  5. Smothers L, Hynan L, Fleming J, Turnage R, Simmang C, Anthony T. Emergency surgery for colon carcinoma. Dis Colon Rectum. 2003;46(1):24–30
  6. Cummins ER, Vick KD, Poole GV. Incurable colorectal carcinoma: the role of surgical palliation. Am Surg. 2004;70(5):433–437
  7. Ruo L, Gougoutas C, Paty PB, Guillem JG, Cohen AM, Wong WD. Elective bowel resection for incurable stage IV colorectal cancer: prognostic variables for asymptomatic patients. J Am Coll Surg. 2003;196(5):722–728
  8. Tebbutt NC, Norman AR, Cunningham D, et al. Intestinal complications after chemotherapy for patients with unresected primary colorectal cancer and synchronous metastases. Gut. 2003;52(4):568–573
  9. Michel P, Roque I, Di Fiore F, et al. Colorectal cancer with non-resectable synchronous metastases: should the primary tumor be resected?. Gastroenterol Clin Biol. 2004;28(5):434–437
  10. Sarela AI, Guthrie JA, Seymour MT, Ride E, Guillou PJ, O'Riordain DS. Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer. Br J Surg. 2001;88(10):1352–1356
  11. Nordic Gastrointestinal Tumor Adjuvant Therapy Group. Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: a randomized trial. J Clin Oncol. 1992;10(6):904–911
  12. Alley PG, McNee RK. Age and sex differences in right colon cancer. Dis Colon Rectum. 1986;29(4):227–229
  13. Wu CS, Tung SY, Chen PC, Kuo YC. Clinicopathological study of colorectal mucinous carcinoma in Taiwan: a multivariate analysis. J Gastroenterol Hepatol. 1996;11(1):77–81
  14. Nozoe T, Anai H, Nasu S, Sugimachi K. Clinicopathological characteristics of mucinous carcinoma of the colon and rectum. J Surg Oncol. 2000;75(2):103–107
  15. Kanemitsu Y, Kato T, Hirai T, et al. Survival after curative resection for mucinous adenocarcinoma of the colorectum. Dis Colon Rectum. 2003;46(2):160–167
  16. Benoist S, Pautrat K, Mitry E, Rougier P, Penna C, Nordlinger B. Treatment strategy for patients with colorectal cancer and synchronous irresectable liver metastases. Br J Surg. 2005;92(9):1155–1160
  17. Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet. 2000;355(9209):1041–1047
  18. Temple LK, Hsieh L, Wong WD, Saltz L, Schrag D. Use of surgery among elderly patients with stage IV colorectal cancer. J Clin Oncol. 2004;22(17):3475–3484
  19. Rapiti E, Verkooijen HM, Vlastos G, et al. Complete excision of primary breast tumor improves survival of patients with metastatic breast cancer at diagnosis. J Clin Oncol. 2006;24(18):2743–2749
  20. Flanigan RC, Yonover PM. The role of radical nephrectomy in metastatic renal cell carcinoma. Semin Urol Oncol. 2001;19(2):98–102
  21. Samarasam I, Chandran BS, Sitaram V, Perakath B, Nair A, Mathew G. Palliative gastrectomy in advanced gastric cancer: is it worthwhile?. ANZ J Surg. 2006;76(1-2):60–63
  22. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649–655

☆ Presented in abstract form at RSM, Coloproctology Section, Overseas Meeting, May 2007, Paris, France, and World Congress of Gastrointestinal Cancers; June 2007, Barcelona, Spain.

PII: S0748-7983(08)00201-1

doi: 10.1016/j.ejso.2008.06.005

European Journal of Surgical Oncology
Volume 35, Issue 2 , Pages 164-167 , February 2009

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