European Journal of Surgical Oncology
Volume 34, Issue 12 , Pages 1277-1284 , December 2008

Axillary recurrence after a tumour-negative sentinel node biopsy in breast cancer patients: A systematic review and meta-analysis of the literature

  • I.M.C. van der Ploeg

      Affiliations

    • Department of Surgery, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 20 512 2467; fax: +31 20 512 2554.
    • ,
  • O.E. Nieweg

      Affiliations

    • Department of Surgery, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    • ,
  • M.C. van Rijk

      Affiliations

    • Department of Surgery, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    • ,
  • R.A. Valdés Olmos

      Affiliations

    • Department of Nuclear Medicine, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    • ,
  • B.B.R. Kroon

      Affiliations

    • Department of Surgery, The Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

,Accepted 29 January 2008.

References 

  1. Veronesi U, Paganelli G, Viale G, et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med. 2003;349:546–553
  2. Nieweg OE, Jansen L, Valdes Olmos RA, et al. Lymphatic mapping and sentinel lymph node biopsy in breast cancer. Eur J Nucl Med. 1999;26:S11–S16
  3. Krag DN. The sentinel node for staging breast cancer: current review. Breast Cancer. 1999;6:233–236
  4. Nieweg OE, van Rijk MC, Valdes Olmos RA, Hoefnagel CA. Sentinel node biopsy and selective lymph node clearance – impact on regional control and survival in breast cancer and melanoma. Eur J Nucl Med Mol Imaging. 2005;32:631–634
  5. Roumen RM, Kuijt GP, Liem IH, van Beek MW. Treatment of 100 patients with sentinel node-negative breast cancer without further axillary dissection. Br J Surg. 2001;88:1639–1643
  6. Badgwell BD, Povoski SP, Abdessalam SF, et al. Patterns of recurrence after sentinel lymph node biopsy for breast cancer. Ann Surg Oncol. 2003;10:376–380
  7. Bedrosian I, Heimbach B, Spitz F, et al. A prospective study of sentinel lymph node biopsy without axillary node dissection for staging patients with breast cancer. Ann Surg Oncol. 2002;12(3):S57
  8. Blanchard DK, Donohue JH, Reynolds C, Grant CS. Relapse and morbidity in patients undergoing sentinel lymph node biopsy alone or with axillary dissection for breast cancer. Arch Surg. 2003;138:482–487
  9. Carcoforo P, Sortini D, Soliani G, Basaglia E, Feggi L, Liboni A. Accuracy and reliability of sentinel node biopsy in patients with breast cancer. Single centre study with long term follow-up. Breast Cancer Res Treat. 2006;95:111–116
  10. Chung MA, Steinhoff MM, Cady B. Clinical axillary recurrence in breast cancer patients after a negative sentinel node biopsy. Am J Surg. 2002;184:310–314
  11. de Kanter AY, Menke-Pluymers MM, Wouters MW, Burgmans I, van Geel AN, Eggermont AM. 5-Year follow-up of sentinel node negative breast cancer patients. Eur J Surg Oncol. 2006;32:282–286
  12. Domenech A, Benitez A, Bajen M, et al. Patients with breast cancer and negative sentinel node biopsy without additional axillary dissection: evolution after a 5-year follow-up. Eur J Nucl Med Mol Imaging. 2006;33(S155):69–80
  13. Guenther JM, Hansen NM, DiFronzo LA, et al. Axillary dissection is not required for all patients with breast cancer and positive sentinel nodes. Arch Surg. 2003;138:52–56
  14. Haid A, Knauer M, Koberle-Wuhrer R, et al. Medium-term follow-up data after sentinel node biopsy alone for breast cancer. Eur J Surg Oncol. 2006;32:1180–1185
  15. Imoto S, Wada N, Murakami K, Hasebe T, Ochiai A, Ebihara S. Prognosis of breast cancer patients treated with sentinel node biopsy in Japan. Jpn J Clin Oncol. 2004;34:452–456
  16. Jeruss JS, Winchester DJ, Sener SF, et al. Axillary recurrence after sentinel node biopsy. Ann Surg Oncol. 2005;12:34–40
  17. Khakpour N, Hunt KK, Kuerer HM, et al. Sentinel lymph node dissection provides axillary control equal to complete axillary node dissection in breast cancer patients with lobular histology and a negative sentinel node. Am J Surg. 2005;190:598–601
  18. Kokke MC, Ernst MF, Eijckeler F, et al. Axillary recurrence after negative sentinel node procedure in breast cancer patients. Eur J Surg Oncol. 2006;32(Suppl 1):S79
  19. Kristen P, Lorenz R, Gross M, et al. Axillary recurrences after sentinel node (SLN) biopsy without complete axillary dissection in breast cancer patients. Br J Cancer. 2005;92:981
  20. Langer I, Marti WR, Guller U, et al. Axillary recurrence rate in breast cancer patients with negative sentinel lymph node (SLN) or SLN micrometastases: prospective analysis of 150 patients after SLN biopsy. Ann Surg. 2005;241:152–158
  21. Leikola J, Saarto T, Joensuu H, et al. Ultrasonography of the axilla in the follow-up of breast cancer patients who have a negative sentinel node biopsy and who avoid axillary clearance. Acta Oncol. 2006;45:571–575
  22. Loza J, Colo F, Nadal J, Viniegra M, Chacon R. Axillary recurrence after sentinel node biopsy for operable breast cancer. Eur J Surg Oncol. 2002;28:897–898
  23. Marrazzo A, Taormina P, David M, et al. The role of sentinel lymph-node biopsy (SLNB) in the treatment of breast cancer. Chir Ital. 2006;58:299–304
  24. Nagashima T, Sakakibara M, Nakano S, et al. Sentinel node micrometastasis and distant failure in breast cancer patients. Breast Cancer. 2006;13:186–191
  25. Naik AM, Fey J, Gemignani M, et al. The risk of axillary relapse after sentinel lymph node biopsy for breast cancer is comparable with that of axillary lymph node dissection: a follow-up study of 4008 procedures. Ann Surg. 2004;240:462–468
  26. Paajanen H, Kilponen VM, Heikkinen J, Sammalkorpi H, Helle M. Feasibility of axillary ultrasound in the quality assessment of sentinel node biopsy in breast cancer surgery. Scand J Surg. 2006;95:195–198
  27. Palesty JA, Foster JM, Hurd TC, Watroba N, Rezaishiraz H, Edge SB. Axillary recurrence in women with a negative sentinel lymph node and no axillary dissection in breast cancer. J Surg Oncol. 2006;93:129–132
  28. Pejavar S, Wilson LD, Haffty BG. Regional nodal recurrence in breast cancer patients treated with conservative surgery and radiation therapy (BCS+RT). Int J Radiat Oncol Biol Phys. 2006;66:1320–1327
  29. Pizzocaro P, Bertagna F, Bosio G, et al. Long-term follow-up of breast cancer patients undergone to mastectomy without axillary dissection after negative sentinel lymph node (SLN) biopsy. Eur J Nucl Med Mol Imaging. 2006;33:S145
  30. Reitsamer R, Peintinger F, Prokop E, Rettenbacher L, Menzel C. 200 Sentinel lymph node biopsies without axillary lymph node dissection – no axillary recurrences after a 3-year follow-up. Br J Cancer. 2004;90:1551–1554
  31. Roka S, Konstantiniuk P, Heck D, et al. Axillary recurrence after sentinel node biopsy. Eur Surg Acta Chir Austriaca. 2002;34(5):280–282
  32. Rosing DK, Dauphine CE, Vargas MP, et al. Axillary regional recurrence after sentinel lymph node biopsy for breast cancer. Am Surg. 2006;72:939–942
  33. Sanjuan A, Vidal-Sicart S, Zanon G, et al. Clinical axillary recurrence after sentinel node biopsy in breast cancer: a follow-up study of 220 patients. Eur J Nucl Med Mol Imaging. 2005;32:932–936
  34. Schrenk P, Hatzl-Griesenhofer M, Shamiyeh A, Waynad W. Follow-up of sentinel node negative breast cancer patients without axillary lymph node dissection. J Surg Oncol. 2001;77:165–170
  35. Schulze T, Mucke J, Markwardt J, Schlag PM, Bembenek A. Long-term morbidity of patients with early breast cancer after sentinel lymph node biopsy compared to axillary lymph node dissection. J Surg Oncol. 2006;93:109–119
  36. Shivers S, Cox C, Leight G, et al. Final results of the Department of Defense multicenter breast lymphatic mapping trial. Ann Surg Oncol. 2002;9:248–255
  37. Sinko M, Rajtar M, Cserni G, Boross G, Tekle Wolde E, Ambrozay E. Axillary recurrence in 292 breast cancer patients with negative sentinel node biopsy and no axillary dissection. Ann Surg Oncol. 2006;224:S272
  38. Snider HC, Rubin E, Henson R. Axillary ultrasonography to detect recurrence after sentinel node biopsy in breast cancer. Ann Surg Oncol. 2006;13:501–507
  39. Snoj M, Bracko M, Zagar I. Axillary recurrence rate in breast cancer patients with negative sentinel lymph node. Croat Med J. 2005;46:377–381
  40. Soni NK, Spillane AJ. Experience of sentinel node biopsy alone in early breast cancer without further axillary dissection in patients with negative sentinel node. ANZ J Surg. 2005;75:292–299
  41. Susini T, Nori J, Vanzi E, et al. Axillary ultrasound scanning in the follow-up of breast cancer patients undergoing sentinel node biopsy. Breast. 2006;16(2):190–196
  42. Swenson KK, Mahipal A, Nissen MJ, et al. Axillary disease recurrence after sentinel lymph node dissection for breast carcinoma. Cancer. 2005;104:1834–1839
  43. Taback B, Hansen N, Conway K, Giuliano A. Recurrence patterns following a negative sentinel lymph node biopsy in patients with early-stage breast cancer. J Clin Oncol. 2004;22(S14):560
  44. Takei H, Suemasu K, Kurosumi M, et al. Recurrence after sentinel lymph node biopsy with or without axillary lymph node dissection in patients with breast cancer. Breast Cancer. 2007;14:16–24
  45. Torrenga H, Fabry H, van der Sijp JR, van Diest PJ, Pijpers R, Meijer S. Omitting axillary lymph node dissection in sentinel node negative breast cancer patients is safe: a long term follow-up analysis. J Surg Oncol. 2004;88:4–7
  46. van der Vegt B, Doting MH, Jager PL, Wesseling J, de Vries J. Axillary recurrence after sentinel lymph node biopsy. Eur J Surg Oncol. 2004;30:715–720
  47. van Wessem KJ, Meijer WS. Sentinel lymph node biopsy in breast cancer: results of intradermal periareolar tracer injection and follow-up of sentinel lymph node-negative patients. Breast. 2004;13:290–296
  48. Veronesi U, Galimberti V, Mariani L, et al. Sentinel node biopsy in breast cancer: early results in 953 patients with negative sentinel node biopsy and no axillary dissection. Eur J Cancer. 2005;41:231–237
  49. Zavagno G, Carcoforo P, Franchini Z, et al. Axillary recurrence after negative sentinel lymph node biopsy without axillary dissection: a study on 479 breast cancer patients. Eur J Surg Oncol. 2005;31:715–720
  50. Ponzone R, Biglia N, Maggiorotto F, et al. Sentinel node dissection as definitive treatment for node negative breast cancer patients. Eur J Surg Oncol. 2003;29:703–706
  51. van Wely BJ, Strobbe LJ, Smidt M, de Kievit IM. Fout negatieve sentinel lymph node biopsie; follow up van 391 sentinel lymph node negatieve patiënten met borstkanker. Ned Tijdschr Geneeskd. 2006;15:1
  52. Grigolato D, Ballarin A, Franchini Z, et al. Sentinel node biopsy: our clinical experience in 232 T1 breast cancers. Eur J Nucl Med Mol Imaging. 2006;33(S2):128–162
  53. de Kanter AY, van Geel AN, Paul MA, et al. Controlled introduction of the sentinel node biopsy in breast cancer in a multi-centre setting: the role of a coordinator for quality control. Eur J Surg Oncol. 2000;26:652–656
  54. Fant JS, Grant MD, Knox SM, et al. Preliminary outcome analysis in patients with breast cancer and a positive sentinel lymph node who declined axillary dissection. Ann Surg Oncol. 2003;10:126–130
  55. Greco M, Agresti R, Cascinelli N, et al. Breast cancer patients treated without axillary surgery: clinical implications and biologic analysis. Ann Surg. 2000;232:1–7
  56. Wright FC, Walker J, Law CH, McCready DR. Outcomes after localized axillary node recurrence in breast cancer. Ann Surg Oncol. 2003;10:1054–1058
  57. Nieweg OE, Tanis PJ, Kroon BB. The definition of a sentinel node. Ann Surg Oncol. 2001;8:538–541
  58. de Boer R, Hillen HF, Roumen RM, Rutten HJ, van der Sangen MJ, Voogd AC. Detection, treatment and outcome of axillary recurrence after axillary clearance for invasive breast cancer. Br J Surg. 2001;88:118–122
  59. Fredriksson I, Liljegren G, Arnesson LG, et al. Consequences of axillary recurrence after conservative breast surgery. Br J Surg. 2002;89:902–908
  60. Recht A, Pierce SM, Abner A, et al. Regional nodal failure after conservative surgery and radiotherapy for early-stage breast carcinoma. J Clin Oncol. 1991;9:988–996

PII: S0748-7983(08)00049-8

doi: 10.1016/j.ejso.2008.01.034

European Journal of Surgical Oncology
Volume 34, Issue 12 , Pages 1277-1284 , December 2008

Article Tools

* Image Usage & Resolution