European Journal of Surgical Oncology
Volume 34, Issue 6 , Pages 620-625 , June 2008

Clinical impact of false-negative sentinel lymph nodes in breast cancer

  • G. Zavagno

      Affiliations

    • Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    • Corresponding Author InformationCorresponding author. Tel/fax: +39 049 8212071.
    • ,
  • P. Del Bianco

      Affiliations

    • Clinical Trials and Biostatistics Unit, Istituto Oncologico Veneto, Via Gattamelata 64, 35128 Padova, Italy
    • ,
  • H. Koussis

      Affiliations

    • Oncologia Medica II, Istituto Oncologico Veneto, Via Gattamelata 64, 35128 Padova, Italy
    • ,
  • G. Artioli

      Affiliations

    • Oncologia Medica I, Istituto Oncologico Veneto, Via Gattamelata 64, 35128 Padova, Italy
    • ,
  • P. Carraro

      Affiliations

    • Chirurgia IV, General Hospital, Treviso, Italy
    • ,
  • G.L. De Salvo

      Affiliations

    • Clinical Trials and Biostatistics Unit, Istituto Oncologico Veneto, Via Gattamelata 64, 35128 Padova, Italy
    • ,
  • R. Mencarelli

      Affiliations

    • Anatomia Patologica, General Hospital of Padova, Via Gabelli 61, 35128 Padova, Italy
    • ,
  • V. Belardinelli

      Affiliations

    • Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    • ,
  • G. Marconato

      Affiliations

    • Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128 Padova, Italy
    • ,
  • D. Nitti

      Affiliations

    • Clinica Chirurgica II, University of Padova, Via Giustiniani 2, 35128 Padova, Italy

,Accepted 2 July 2007.

References 

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  2. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg. 1994;220:391–401
  3. Kelley MC, Hansen N, McMasters KM. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Am J Surg. 2004;188:49–61
  4. Zavagno G, De Salvo GL, Scalco G, et al. A randomized clinical trial on sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer. Results of the Sentinella/Givom trial. Ann Surg. 2008;247(2):207–213
  5. Wright FC, Walker J, Law CH, McCready DR. Outcomes after localized axillary node recurrence in breast cancer. Ann Surg Oncol. 2003;10:1054–1058
  6. Veronesi U, Paganelli G, Viale G, et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med. 2003;349:546–553
  7. Zavagno G, De Salvo GL, Casara D, et al. Sentinel node biopsy for breast cancer: is it already a standard of care? A survey of current practice in an Italian region. BMC Cancer. 2004;4:2
  8. Wada N, Imoto S, Yamauchi C, Hasebe T, Ochiai A, Ebihara S. Correlation between concordance of tracers, order of harvest, and presence of metastases in sentinel lymph nodes with breast cancer. Ann Surg Oncol. 2005;12:1–7
  9. Wong SL, Edwards MJ, Chao C, et al. Sentinel lymph node biopsy for breast cancer: impact of the number of sentinel nodes removed on the false-negative rate. J Am Coll Surg. 2001;192:684–689
  10. Martin RCG, Chagpar A, Scoggins CR, et al. Clinicopathologic factors associated with false-negative sentinel lymph-node biopsy in breast cancer. Ann Surg. 2005;241:1005–1015
  11. Tafra L, Lannin DR, Swanson MS, et al. Multicenter trial of sentinel node biopsy for breast cancer using both technetium sulfur colloid and isosulfan blue dye. Ann Surg. 2001;233:51–59
  12. Goyal A, Newcombe RG, Chhabra A, Mansel RE. Factors affecting failed localization and false-negative rates of sentinel node biopsy in breast cancer. Results of the ALMANAC validation phase. Breast Cancer Res Treat. 2006;99:203–208
  13. Greco M, Gennaro M, Valagussa P, et al. Impact of nodal status on indication for adjuvant treatment in clinically node negative breast cancer. Ann Oncol. 2000;11:1079–1080
  14. Catzeddu T, Bertelli G, Del Mastro L, Venturini M. Sentinel lymph node biopsy in breast cancer patients: the medical oncology perspective. J Surg Oncol. 2004;85:129–132
  15. Houvenaeghel G, Martino M, Jacquemier J, et al. Risk of stage underestimation of breast cancer by sentinel lymph node biopsy method. Bull Cancer. 2003;90:467–473
  16. Nano MT, Kollias J, Farshid G, Gill PG, Bochner M. Clinical impact of false-negative sentinel node biopsy in primary breast cancer. Br J Surg. 2002;89:1430–1434
  17. Badgwell BD, Povoski SP, Abdessalam SF, et al. Patterns of recurrence after sentinel lymph node biopsy for breast cancer. Ann Surg Oncol. 2003;10:376–380
  18. Blanchard DK, Donohue JH, Reynolds C, Grant CS. Relapse and morbidity in patients undergoing sentinel lymph node biopsy alone or with axillary dissection for breast cancer. Arch Surg. 2003;138:482–487
  19. Reitsamer R, Peintiger F, Prokop E, Rettenbacher L, Menzel C. 200 sentinel lymph node biopsies without axillary lymph node dissection. No axillary recurrences after a 3-year follow-up. Br J Cancer. 2004;90:1551–1554
  20. Zavagno G, Carcoforo P, Franchini Z, et al. Axillary recurrence after negative sentinel lymph node biopsy without axillary dissection: a study on 479 breast cancer patients. Eur J Surg Oncol. 2005;31:715–720
  21. Veronesi U, Galimberti V, Mariani L, et al. Sentinel node biopsy in breast cancer: early results in 953 patients with negative sentinel node biopsy and no axillary dissection. Eur J Cancer. 2005;41:231–237

PII: S0748-7983(07)00276-4

doi: 10.1016/j.ejso.2007.07.003

European Journal of Surgical Oncology
Volume 34, Issue 6 , Pages 620-625 , June 2008

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