European Journal of Surgical Oncology
Volume 32, Issue 7 , Pages 719-724 , September 2006

Clinical outcome and service implications of screening women at increased breast cancer risk from a family history

  • G.P.H. Gui

      Affiliations

    • Department of Academic Surgery and the Breast Diagnostic Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • Corresponding Author InformationCorresponding author. Tel.: +44 20 7808 2783; fax: +44 20 7808 2673.
    • ,
  • G. Kadayaprath

      Affiliations

    • Department of Academic Surgery and the Breast Diagnostic Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • ,
  • N. Darhouse

      Affiliations

    • Department of Academic Surgery and the Breast Diagnostic Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • ,
  • J. Self

      Affiliations

    • Department of Academic Surgery and the Breast Diagnostic Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • ,
  • A. Ward

      Affiliations

    • Department of Academic Surgery and the Breast Diagnostic Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • ,
  • R. A'Hern

      Affiliations

    • Department of Information Technology and Statistics, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom
    • ,
  • R. Eeles

      Affiliations

    • Translational Cancer Genetics Team, Institute of Cancer Research and Cancer Genetics Unit, Royal Marsden NHS Foundation Trust, Fulham Road, London SW3 6JJ, United Kingdom

,Accepted 3 May 2006.

References 

  1. Easton D, Peto J. The contribution of inherited predisposition to cancer incidence. Cancer Surv. 1990;9:395–416
  2. Claus EB, Risch N, Thompson WD. Genetic analysis of breast cancer in the cancer and steroid hormone study. Am J Hum Genet. 1991;48:232–242
  3. Easton DF, Ford D, Bishop DT. Breast Cancer Linkage Consortium, breast and ovarian cancer incidence in BRCA-1 mutation carriers. Am J Hum Genet. 1995;56:265–271
  4. Struewing JP, Hartge P, Wacholder S, et al. The risk of cancer associated with specific mutations of BRCA-1 and BRCA-2 among Ashkenazi Jews. N Engl J Med. 1997;336:1401–1408
  5. Thorlacius S, Struewing JP, Hartge P, et al. Population-based study of risk of breast cancer in carriers of BRCA-2 mutations. Lancet. 1998;352:1737–1739
  6. Eccles DM, Evans DG, Mackay J. Guidelines for a genetic risk based approach to advising women with a family history of breast cancer. UK Cancer Family Study Group (UKCFSG). J Med Genet. 2000;37:203–209
  7. Sauven P. Association of Breast Surgery Family History Guidelines Panel. Guidelines for the management of women at increased familial risk of breast cancer. Eur J Cancer. 2004;40:653–665
  8. Familial breast cancer. The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care. In: National Institute of Clinical Excellence (NICE) guidelines 2004. London: Hobbs; 2004;p. 1–9www.nice.org.uk/CG014NICEguideline
  9. Lloyd S, Watson M, Waites B, et al. Familial breast cancer: a controlled study of risk perception, psychological morbidity and health beliefs in women attending for genetic counselling. Br J Cancer. 1996;74:482–487
  10. Lerman C, Lustbader E, Rimer B, et al. Effects of individualised breast cancer risk counselling: a randomised trial. J Natl Cancer Inst. 1995;87:286–292
  11. Hopwood P, Keeling F, Long A, Pool C, Evans G, Howell A. Psychological support needs for women at high genetic risk of breast cancer: some preliminary indicators. Psychooncology. 1998;7:402–412
  12. Kollias J, Sibbering RW, Blamey RW, et al. Screening women less than 50 years with a family history of breast cancer. Eur J Cancer. 1998;34:878–883
  13. Lalloo F, Boggis CRM, Evans DGR, Shenton A, Threlfall AG, Howell A. Screening by mammography, women with a family history of breast cancer. Eur J Cancer. 1998;34:937–940
  14. MacMillan RD. Screening women with a family history of breast cancer – results from the British Familial Breast Cancer Group. Eur J Surg Oncol. 2000;26:149–152
  15. Gui GPH, Hogben RFK, Walsh G, A'Hern R, Eeles R. The incidence of breast cancer from screening women according to predicted family history risk: does annual clinical examination add to mammography. Eur J Cancer. 2001;37:1668–1673
  16. Fletcher SW, Black W, Harris R, Ramer BK, Shapiro S. Report of the international workshop on screening for breast cancer. J Natl Cancer Inst. 1993;85:1644
  17. Antman K, Schea S. Screening mammography under age 50. JAMA. 1999;281:1470–1472
  18. Olsen O, Gotzsche PC. Cochrane review on screening for breast cancer with mammography. Lancet. 2001;358:1340–1342
  19. Miller AB, To T, Baines CJ, Wall C. The Canadian National Breast Screening Study-1: breast cancer mortality after 11 to 16 years of follow-up. A randomized screening trial of in women aged 50–59 years. Ann Intern Med. 2002;137:305–312
  20. Freedman DA, Petitti DB, Robins JM. On the efficacy of screening for breast cancer. Int J Epidemiol. 2004;33:43–55
  21. <www.cancer.org/PED/content/PtD_2_3x_Mammography_and_ Other_Breast_Imaging_Procedures.asp?sitearea=PED>.
  22. Burke W, Daly M, Garber J, et al. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. JAMA. 1997;277:997–1003
  23. Lucassen A, Watson E, Harcourt J, Rose P, O'Grady J. Guidelines for referral to a regional genetics services: GP's respond by referring more appropriate cases. Fam Pract. 2001;18:135–140
  24. Emery J, Murphy M, Lucassen A. Heritage free cancer – the evidence for current recommended management. Lancet Oncol. 2000 May;9–16
  25. Patnick J. NHS Breast Screening Programme – review 1994. In: The House of Commons Health Select Committee Report into Breast Cancer Services. 1994.
  26. Quality assurance guidelines for breast screening radiology. In: Liston J, Wilson R, editors. National Health Breast Screening Programme (NHSBSP), publication number 59. 2005.
  27. Elmore JG, Wells CK, Howard DH, Finstein AR. The impact of clinical history on mammographic interpretation. JAMA. 1997;277:49–52
  28. Whitehouse PA, Baber Y, Brown G, Moskovic E, King DM, Gui GPH. The use of ultrasound by breast surgeons in outpatients: an accurate extension of clinical diagnosis. Eur J Surg Oncol. 2001;27:611–616
  29. Brain K, Gray J, Norman P, et al. Randomised trial of a specialist genetic assessment service for familial breast cancer. J Natl Cancer Inst. 2000;92:1345–1351
  30. Gray J, Brain K, Norman P, et al. A model protocol evaluating the introduction of genetic assessment for women with a family history of breast cancer. J Med Genet. 2000;27:192–196
  31. Ong G, Austoker J, Brett J, Boyce A, Jepson C, Ingstrom PF. Breast screening: adverse psychological consequences one month after placing women on early recall because of a diagnostic uncertainty. A multi-centre study. J Med Screen. 1997;4:158–168
  32. Brett J, Austoker J, Ong GJ. Do women who undergo further investigation for breast screening suffer adverse psychological consequences? A follow-up multi-centre study comparing different breast screening result groups five months after their last breast screening appointment. J Public Health Med. 1998;20:396–403
  33. Lerman C, Trock B, Rimer BK, Boyce A, Jepson C, Ingstrom PF. Psychological and behavioural implications of abnormal mammograms. Ann Intern Med. 1991;114:657–661
  34. Olsson P, Armelius K, Nordahl G, Lenner P, Westman G. Women with false positive screening mammograms; how do they cope?. J Med Screen. 1999;6:89–93
  35. Gilbert FJ, Cordiner CM, Affleck IR, Hood DB, Mathieson D, Walker LG. Breast screening: the psychological sequelae of false-positive recall in women with and without family history of breast cancer. Eur J Cancer. 1998;34:2010–2014
  36. Brett J, Bankhead C, Henderson B, Watson E, Austoker J. The psychological impact of mammographic screening. A systematic review. Psychooncology. 2005;14:917–938
  37. Raffle AE. Informed participation in screening is essential. Br Med J. 1997;314:1760–1763

☆ This work was given as an oral presentation at the British Association of Surgical Oncology Scientific Meeting at the Royal College of Surgeons of England, 14–15 November 2005.

PII: S0748-7983(06)00210-1

doi: 10.1016/j.ejso.2006.05.002

European Journal of Surgical Oncology
Volume 32, Issue 7 , Pages 719-724 , September 2006

Article Tools